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MacVector and Mavericks
Read more: MacVector and MavericksOS X Mavericks was released last week. As usual we’d been testing MacVector on the prerelease developer previews. We did come across a few issues, however, these all seem to be working fine now it’s officially released. So far we’ve done plenty of informal testing with MacVector 12.7.5 and we’ve not come across any major…
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MacVector 12.7 Training Workshop, LMB, Cambridge
Read more: MacVector 12.7 Training Workshop, LMB, CambridgeWhen: Thursday 19th September, 2013, 2:00 – 4:00, Where: Max Perutz Lecture Theatre, LMB Chris Lindley of MacVector, Inc. will be giving a workshop for both novice and advanced users of MacVector, reviewing both basic and advanced functions in MacVector. In particular, he will highlight the new functionality introduced over the past two years to MacVector.…
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The oldest entries in Genbank? Some fun for Labor day.
Read more: The oldest entries in Genbank? Some fun for Labor day.Inspired by some tweets from @ewanbirney, because I’m waiting for lunch and because it’s Labor Day I used the Entrez tool to find the oldest entries (using the publication date field) in Genbank. For proteins there’s a single hit in 1979 For NA there’s 12 hits from 1982: Nothing useful here and it’s probably not…
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101 things you (maybe) didn’t know about MacVector: #32 – Understanding The Sequence Find Function
Read more: 101 things you (maybe) didn’t know about MacVector: #32 – Understanding The Sequence Find FunctionWe get quite a lot of support requests from users unsure of how to use the Find functionality in MacVector. It has changed somewhat over the years to try to simplify the interface, but there are still a few things to be aware of. You can invoke the Find function by bringing a sequence window…
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101 things you (maybe) didn’t know about MacVector: #31 – Exporting Subsequences To Excel
Read more: 101 things you (maybe) didn’t know about MacVector: #31 – Exporting Subsequences To ExcelMany MacVector users like to keep track of primers used in the lab by maintaining them in a MacVector Nucleic Acid Subsequence file. I discussed this in a previous post and later described how to create a primer “database” from a Microsoft Excel file. We recently had a support request asking how to do the…
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101 things you (maybe) didn’t know about MacVector: #30 – Submitting Sequences To GenBank using Sequin
Read more: 101 things you (maybe) didn’t know about MacVector: #30 – Submitting Sequences To GenBank using SequinNote: while preparing this blog post we discovered a bug in MacVector 12.7.4 that prevents submission using the exact steps shown here. Be sure you are using MacVector 12.7.5 or later which has the bug fixed. If you are using an earlier version, send an e-mail to support@macvector.com and we’ll send you the details of…
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101 things you (maybe) didn’t know about MacVector: #29 – Option-Click to Close All Windows
Read more: 101 things you (maybe) didn’t know about MacVector: #29 – Option-Click to Close All WindowsIf you are like me, you often find yourself with many, many windows open while using MacVector. Sometimes you just want to get rid of everything and start all over again with a different project. You can always just quit MacVector and start again, but there is an easier way: Hold down the option key…
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101 things you (maybe) didn’t know about MacVector: #28 – Identifying Methylation Blocked Restriction Sites
Read more: 101 things you (maybe) didn’t know about MacVector: #28 – Identifying Methylation Blocked Restriction SitesA big thanks to Jeffrey Dvorin at Boston Children’s Hospital for this great suggestion. Most common laboratory strains of E. coli contain a number of methylase enzymes that modify DNA residues, preventing certain restriction enzymes from cutting DNA isolated from those strains. The two most relevant enzymes are the Dam methylase that methylates the A…
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101 things you (maybe) didn’t know about MacVector: #27 – Documenting Gibson Assemblies
Read more: 101 things you (maybe) didn’t know about MacVector: #27 – Documenting Gibson AssembliesWe’ve had a few MacVector users ask us recently if MacVector can be used to create constructs using the increasingly popular “Gibson Assembly” method. For those who are not familiar with this method, it was first described in 2009 by Daniel Gibson of the J. Craig Venter Institute. They showed that you can assemble multiple…
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MacVector 12.7 Training Workshop, Weatherall Institute for Molecular Medicine
Read more: MacVector 12.7 Training Workshop, Weatherall Institute for Molecular MedicineWhen: Tuesday, 23rd of April 2013, 14:00 until 16:00 Where: WIMM Seminar Room, WIMM Chris Lindley of MacVector, Inc. will be giving a workshop for both novice and advanced users of MacVector, reviewing both basic and advanced functions in MacVector. In particular, he will highlight the new functionality introduced over the last two years to MacVector.…